Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00017) | ||||||
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| BTS Name |
Apolipoprotein A-I
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| Synonyms |
Apo-AI; ApoA-I; Apolipoprotein A1
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| BTS Type |
Protein
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| Family |
Apolipoprotein A1/A4/E family
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| Gene Name |
APOA1
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| Organism |
Homo sapiens (Human)
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| Function |
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
MKAAVLTLAVLFLTGSQARHFWQQDEPPQSPWDRVKDLATVYVDVLKDSGRDYVSQFEGS
ALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAK VQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHV DALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQ GLLPVLESFKVSFLSALEEYTKKLNTQ |
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| Sequence Length |
267
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Affibody anti-Apo-A-1 clone 24:4 | Research | Binder | Kd: 1000 nM | Tools for specific binding to different target proteins | [1] | |