Details of the SBP

General Information of Synthetic Binding Protein (SBP) (ID: SBP000269)
SBP Name	Bicyclic peptide anti-ERBB3 H33
Synonyms	Bicyclic peptide H33
Molecular Weight	2.0 kDa
Design Method	Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status	Research
Sequence Length	17
SBP Sequence	>Bicyclic peptide anti-ERBB3 H33 ACYLQDPNCDWWGPYCG
3D Structure
	Computationally Modelled Structure
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Protein Scaffold Information of This SBP
Scaffold ID	PS017 Scaffold Info
Scaffold Name	Bicyclic peptide
Scaffold Class	Non-Antibody
Fold Type	Loops

Binding Target(s) of This SBP (BTS)

BTS Name	Details	Mechanism	Application	Affinity	Research Organization	Ref
Receptor tyrosine-protein kinase erbB-3	BTS Info	Inhibitor	Cancers [ICD-11: 2D4Z]	Kd: 304 nM	Lausanne Federal Institute of Technology