Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000259) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Bicyclic peptide anti-TNF-alpha anticachexin C1
|
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| Synonyms |
Anticachexin C1
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Sequence Length | 25 | |||||
| SBP Sequence |
>Bicyclic peptide anti-TNF-alpha anticachexin C1
[Phg]Y[d-Ala]LY[d-Phe]G[d-Lys]H[Dap] |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS017 | [1] | ||||
| Scaffold Name | Bicyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Tumor necrosis factor | Inhibitor | Tools for inhibiting protein-protein interactions | Kd: 450 nM | Department of Chemistry and Biochemistry, The Ohio State University | [1] | |