General Information of Synthetic Binding Protein (SBP) (ID: SBP000258)
SBP Name
Bicyclic peptide anti-Grb2 clone 1
Synonyms
BC1
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Sequence Length 11
Protein Scaffold Information of This SBP
Scaffold ID PS017
Scaffold Info
[1]
Scaffold Name Bicyclic peptide
Scaffold Class Non-Antibody
Fold Type Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Growth factor receptor-bound protein 2
BTS Info
Inhibitor Tools for promoting phosphotyrosine mimicry and cellular uptake N.A. Department of Chemistry, Tufts University [1]
References
1 A bicyclic peptide scaffold promotes phosphotyrosine mimicry and cellular uptake. Bioorg Med Chem. 2014 Nov 15;22(22):6387-91.