Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000255) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Bicyclic peptide anti-EphA2 clone 6065
|
|||||
| Synonyms |
BCY6065
|
|||||
| Molecular Weight | 2.1 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| Sequence Length | 19 | |||||
| SBP Sequence |
>Bicyclic peptide anti-EphA2 clone 6065
ARDCPLVNPLCLHPGWTCA |
|||||
| 3D Structure | ||||||
| Computationally Modelled Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS017 | [1] | ||||
| Scaffold Name | Bicyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Ephrin type-A receptor 2 | Binder | Solid tumour/cancer [ICD-11: 2A00-2F9Z] | Kd: 5.8 nM | Babraham Research Campus | [1] | |