Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000253) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Bicyclic peptide anti-EphA2 clone 6044
|
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| Synonyms |
BCY6044
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| Molecular Weight | 1.5-3 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| Sequence Length | 30 | |||||
| SBP Sequence |
>Bicyclic peptide anti-EphA2 clone 6044
[beta-Ala][Sar][Sar][Sar][Sar][Sar][Sar][Sar][Sar][Sar][Sar] H[d-Asp]VPC[2-aminoisobutyric acid][1-naphthylalanine]G [2-a minoisobutyric acid]F[1-naphthylalanine]CP[tert-butyl glycin e]N[homoarginine]P[d-Asp]C |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS017 | [1] | ||||
| Scaffold Name | Bicyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Ephrin type-A receptor 2 | Binder | Solid tumour/cancer [ICD-11: 2A00-2F9Z] | Kd: 2.8 nM | Babraham Research Campus | [1] | |