Details of the SBP
General Information of Synthetic Binding Protein (SBP) (ID: SBP000247) | ||||||
---|---|---|---|---|---|---|
SBP Name |
Affilin anti-HPV16 D1C14
|
|||||
Synonyms |
Affilin D1C14
|
|||||
Molecular Weight | 20.9 kDa | |||||
Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
Expression System | Escherichia coli BL21 (DE3); Escherichia coli NovaBlue (DE3) | |||||
Selection Method | Phage display | |||||
Highest Status | Research | |||||
Sequence Length | 176 | |||||
SBP Sequence |
>Affilin anti-HPV16 D1C14
GCICFGEDRAFQGRAYRCRTDCPNLQPYFSRCNSIKVGSGCWMIYERPNYQGHQYFLRRG EYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLTE IHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLYLE |
|||||
3D Structure | ||||||
Computationally Modelled Structure | ||||||
Click to Save PDB File | ||||||
Template Name | Gamma-B-crystallin | |||||
Protein Scaffold Information of This SBP | ||||||
---|---|---|---|---|---|---|
Scaffold ID | PS005 | [1] | ||||
Scaffold Name | Affilin | |||||
Scaffold Class | Non-Antibody | |||||
Fold Type | Beta-Sheets + Beta-Turns + Loops | |||||
Binding Target(s) of This SBP (BTS) |
---|
BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
---|---|---|---|---|---|---|
Protein E7 | Binder | Cervical cancer [ICD-11: 2C77.Z] | Kd: 70 nM | Martin Luther University Halle-Wittenberg | [1] | |