General Information of Synthetic Binding Protein (SBP) (ID: SBP000222)
SBP Name
Peptide aptamer anti-SARS-CoV-2
Synonyms
Anti-SARS-CoV-2 Peptide aptamer
Molecular Weight 14.0 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Highest Status Research
Sequence Length 127
SBP Sequence
>Peptide aptamer anti-SARS-CoV-2
MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGAKTFLDKFNHEAEDLFYQPCKMIAPI
LDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
FLDANLA
3D Structure
Computationally Modelled Structure
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Template Name Thioredoxin (TrxA)
Protein Scaffold Information of This SBP
Scaffold ID PS051
Scaffold Info
[1]
Scaffold Name Peptide aptamer
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Spike glycoprotein
BTS Info
Binder SARS-CoV-2 infection (COVID-19) [ICD-11: XN109] N.A. Tezpur University [1]
References
1 Designing of peptide aptamer targeting the receptor-binding domain of spike protein of SARS-CoV-2: an in silico study. Mol Divers. 2021 Jan 2;1-13.