General Information of Synthetic Binding Protein (SBP) (ID: SBP000219)
SBP Name
Peptide aptamer anti-Rep A22
Synonyms
Peptide aptamer A22
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System T1 transgenic lines
Selection Method Yeast two-hybrid screen
Highest Status Research
SBP Sequence
>Inserted sequence
CRTRGCGCHLCRMLSQFTGG
Template Name Thioredoxin (TrxA)
Protein Scaffold Information of This SBP
Scaffold ID PS051
Scaffold Info
[1]
Scaffold Name Peptide aptamer
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Replication-associated protein
BTS Info
Binder Tomato yellow leaf curl virus infection; Tomato mottle virus infection N.A. North Carolina State University [1]
References
1 Peptide aptamers that bind to geminivirus replication proteins confer a resistance phenotype to tomato yellow leaf curl virus and tomato mottle virus infection in tomato. J Virol. 2013 Sep;87(17):9691-706.