General Information of Synthetic Binding Protein (SBP) (ID: SBP000214)
SBP Name
Peptide aptamer anti-SmpB clone 1
Synonyms
PA-1
Molecular Weight 21.3 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli BL21 (DE3)
Selection Method Bacterial two-hybrid system
Highest Status Research
SBP Sequence
>Inserted sequence
GGVTFLVNTYPNGVQSRAGG
3D Structure
Computationally Modelled Structure
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Template Name Staphylococcus aureus nuclease
Protein Scaffold Information of This SBP
Scaffold ID PS051
Scaffold Info
[1]
Scaffold Name Peptide aptamer
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
SsrA-binding protein
BTS Info
Inhibitor Aeromonas veronii infection Kd: 691 nM Hainan University [1]
References
1 Targeting Inhibition of SmpB by Peptide Aptamer Attenuates the Virulence to Protect Zebrafish against Aeromonas veronii Infection. Front Microbiol. 2017 Sep 13;8:1766.