Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000208) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Peptide aptamer anti-PrP clone 8-46K
|
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| Synonyms |
PA8-46K
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Selection Method | Yeast two-hybrid screen | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>Inserted sequence
ARFEYLRDGYKVWRFT |
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| Template Name | Thioredoxin (TrxA) | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS051 | [1] | ||||
| Scaffold Name | Peptide aptamer | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Major prion protein | Binder | Prion diseases [ICD-11: 8E0Z] | N.A. | University of Calgary | [1] | |