Details of the SBP

General Information of Synthetic Binding Protein (SBP) (ID: SBP000186)
SBP Name
Peptide aptamer anti-HBV C1-1
Synonyms
Peptide aptamer core protein C1-1
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Mammalian cells
Selection Method Yeast two-hybrid screen
Highest Status Research
SBP Sequence
>Inserted sequence
SFYSVLFLWGTCGGFSHSWY
Protein Scaffold Information of This SBP
Scaffold ID PS051
Scaffold Info
[1] , [2]
Scaffold Name Peptide aptamer
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Capsid protein
BTS Info
Inhibitor Hepatitis B virus infection [ICD-11: XN0GA] N.A. Angewandte Tumorvirologie [1] , [2]
References
1 Peptide aptamers targeting the hepatitis B virus core protein: a new class of molecules with antiviral activity. Oncogene. 2001 Oct 4;20(45):6579-86.
2 Peptide aptamers with biological and therapeutic applications. Curr Med Chem. 2011;18(27):4215-22.