General Information of Synthetic Binding Protein (SBP) (ID: SBP000112)
SBP Name
DARPin anti-FAP/CD40 MP0317
Synonyms
DARPin MP0317
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS027
Scaffold Info
[1] , [2]
Scaffold Name DARPin
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Tumor necrosis factor receptor superfamily member 5
BTS Info
Agonist Tumors [ICD-11: XH1N44] N.A. Molecular Partners [1] , [2]
Prolyl endopeptidase FAP
BTS Info
Agonist Tumors [ICD-11: XH1N44] N.A. Molecular Partners [1] , [2]
References
1 Beyond Antibodies: The DARPin ? Drug Platform. BioDrugs. 2020 Aug;34(4):423-433.
2 Molecular Partners. Product Development Pipeline. 2021.