Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000098) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Anticalin anti-CTLA-4 Lcn2m7.1
|
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| Synonyms |
Anticalin Lcn2m7.1
|
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| Molecular Weight | 27.1 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Selection Method | Escherichia coli display and Fluorescence-activated cell sorting | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS011 | [1] | ||||
| Scaffold Name | Anticalin | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | One Alpha-Helix + Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Cytotoxic T-lymphocyte protein 4 | Blocker | Research tool | Kd: 190 nM | Technical University of Munich | [1] | |