General Information of Binding Target of SBP (BTS) (ID: ST00519)
BTS Name
WW1 peptide
Synonyms
Peptide GTPPPPYTVG
BTS Type
Protein
Organism
Homo sapiens (Human)
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
WW domain anti-peptide mutant L30K Research Binder Kd: 40000 nM Tools for studying peptide recognition
SBP Info
[1]
WW domain anti-peptide mutant PK1 Research Binder Kd: 102000 nM Tools for studying peptide recognition
SBP Info
[2]
WW domain anti-peptide mutant PK2 Research Binder Kd: 37000 nM Tools for studying peptide recognition
SBP Info
[2]
WW domain anti-peptide mutant PK3 Research Binder Kd: 3300 nM Tools for studying peptide recognition
SBP Info
[2]
WW domain anti-peptide mutant PK4 Research Binder Kd: 98000 nM Tools for studying peptide recognition
SBP Info
[2]
References
1 Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope. J Mol Biol. 2001 Dec 14;314(5):1147-56.
2 Evolution of binding affinity in a WW domain probed by phage display. Protein Sci. 2000 Dec;9(12):2366-76.