General Information of Binding Target of SBP (BTS) (ID: ST00448)
BTS Name
SrcA subgroup Yes-Src-homology 2
Synonyms
Yes SH2
BTS Type
Protein
Organism
Homo sapiens (Human)
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Monobody anti-Fgr-SH2/Src-SH2/Yes-SH2 clone 1 Research Inhibitor Kd: 456 nM Tools for dissecting SFK functions in normal development and signaling
SBP Info
[1]
Monobody anti-Src-SH2/Yes-SH2 clone 2 Research Inhibitor Kd: 294 nM Tools for dissecting SFK functions in normal development and signaling
SBP Info
[1]
Monobody anti-Yes SH2 clone 3 Research Inhibitor Kd: 272 nM Tools for dissecting SFK functions in normal development and signaling
SBP Info
[1]
Monobody anti-Yes-SH2/Src-SH2 clone 1 Research Inhibitor Kd: 338 nM Tools for dissecting SFK functions in normal development and signaling
SBP Info
[1]
References
1 Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies. J Mol Biol. 2017 May 5;429(9):1364-1380.