General Information of Binding Target of SBP (BTS) (ID: ST00400)
BTS Name
Tubulin
Synonyms
Tubulin
BTS Type
Protein
Organism
Homo sapiens (Human)
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
DARPin anti-Tubulin A-C2 Research Binder Kd: 0.82 nM Tools as an improved affinity for tubulin
SBP Info
[1]
DARPin anti-Tubulin D1 Research Binder Kd: 127 nM Tools for microtubule disassembly
SBP Info
[2], [1]
DARPin anti-Tubulin TM-3 Research Binder Kd: 0.9 nM Research tool
SBP Info
[1]
References
1 Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin. Sci Rep. 2016 Jul 6;6:28922.
2 Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin. Nat Commun. 2017 Jul 10;8(1):70.