General Information of Binding Target of SBP (BTS) (ID: ST00388)
BTS Name
Leukocidin
Synonyms
Staphylococcus aureus leukocidin
BTS Type
Protein
Organism
Staphylococcus aureus
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Centyrin anti-Leukocidin/Toxin-HlgA SM1S449 Research Inhibitor Kd: 32.4 nM Staphylococcus aureus [ICD-11: XN6BM]
SBP Info
[1]
Centyrin anti-Leukocidin/Toxin-HlgA SM1S452 Research Inhibitor Kd: 20.1 nM Staphylococcus aureus [ICD-11: XN6BM]
SBP Info
[1]
Centyrin anti-leukocidins SM1S163 Research Inhibitor Kd: 5.0 nM Staphylococcus aureus [ICD-11: XN6BM]
SBP Info
[1]
Centyrin anti-leukocidins SM1S17 Research Inhibitor Kd: 12.7 nM Staphylococcus aureus [ICD-11: XN6BM]
SBP Info
[1]
Centyrin anti-leukocidins SM1S26 Research Inhibitor Kd: 11.3 nM Staphylococcus aureus [ICD-11: XN6BM]
SBP Info
[1]
References
1 Identification of biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus. Sci Transl Med. 2019 Jan 16;11(475):eaat0882.