Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00183) | ||||||
|---|---|---|---|---|---|---|
| BTS Name |
Intimin
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| Synonyms |
Attaching and effacing protein; Eae protein; Gamma-intimin
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| BTS Type |
Protein
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| Family |
Intimin/invasin family
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| Gene Name |
eae
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| Organism |
Escherichia coli O157:H7
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| Function |
Necessary for the production of attaching and effacing lesions on tissue culture cells.
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
MITHGCYTRTRHKHKLKKTLIMLSAGLGLFFYVNQNSFANGENYFKLGSDSKLLTHDSYQ
NRLFYTLKTGETVADLSKSQDINLSTIWSLNKHLYSSESEMMKAAPGQQIILPLKKLPFE YSALPLLGSAPLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSR SLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKM LAFGQVGARYIDSRFTANLGAGQRFFLPANMLGYNVFIDQDFSGDNTRLGIGGEYWRDYF KSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLIYEQYYGDNVAL FNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKSWSQQIE PQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTEHSTQKIQLIVKSKY GLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNIYKVTARAYDRNGNSSN NVQLTITVLSNGQVVDQVGVTDFTADKTSAKADNADTITYTATVKKNGVAQANVPVSFNI VSGTATLGANSAKTDANGKATVTLKSSTPGQVVVSAKTAEMTSALNASAVIFFDQTKASI TEIKADKTTAVANGKDAIKYTVKVMKNGQPVNNQSVTFSTNFGMFNGKSQTQATTGNDGR ATITLTSSSAGKATVSATVSDGAEVKATEVTFFDELKIDNKVDIIGNNVRGELPNIWLQY GQFKLKASGGDGTYSWYSENTSIATVDASGKVTLNGKGSVVIKATSGDKQTVSYTIKAPS YMIKVDKQAYYADAMSICKNLLPSTQTVLSDIYDSWGAANKYSHYSSMNSITAWIKQTSS EQRSGVSSTYNLITQNPLPGVNVNTPNVYAVCVE |
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| Sequence Length |
934
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Human VH dAb anti-MBP-intimin VH428-4 | Research | Binder | Kd: 2590 nM | Research tool | [1] | |
| Human VH dAb anti-MBP-intimin VHB82(SS)-8 | Research | Binder | Kd: 5230 nM | Research tool | [1] | |
| VL dAb anti-MBP-intimin VL383(SS)-4 | Research | Binder | Kd: 227 nM | Research tool | [1] | |
| VL dAb anti-MBP-intimin VL383(SS)-5 | Research | Binder | Kd: 252 nM | Research tool | [1] | |
| VL dAb anti-MBP-intimin VL383(SS)-7 | Research | Binder | Kd: 11500 nM | Research tool | [1] | |