Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP003594) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Macrocyclic peptide anti-retromer RT-L4
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| Synonyms |
Macrocyclic peptide RT-L4
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| Molecular Weight | 2 kDa | |||||
| Design Method | de novo protein design | |||||
| Highest Status | Research | |||||
| Sequence Length | 16 | |||||
| SBP Sequence |
>Macrocyclic peptide anti-retromer RT-L4
(AcL)YWISNSWTTYRYVSTC |
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| Sequence Description | (AcL)Y and Cys from a thioether linkage. | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS044 | [1] | ||||
| Scaffold Name | Macrocyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Vacuolar protein sorting-associated protein 35-Vacuolar protein sorting-associated protein 26-Vacuolar protein sorting-associated protein 29 | Inhibitor | Tool for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex | Kd: 273 nM | The University of Queensland | [1] | |