General Information of Synthetic Binding Protein (SBP) (ID: SBP003533)
SBP Name
vNAR anti-HSA huE06 v1.2
Synonyms
vNAR huE06 v1.2
Molecular Weight 11.3 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Sequence Length 103
SBP Sequence
>vNAR anti-HSA huE06 v1.2
TRVDQSPSSLSASVGDRVTITCVLTDTSYPLYSTYWYQQKPGSSNKEQISISGRYSESVN
SGSKSFTLTISSLQPEDFATYYCRAMGTNIWTGDGAGTKVEIK
3D Structure
Computationally Modelled Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS065
Scaffold Info
[1]
Scaffold Name vNAR
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Albumin
BTS Info
Neutralizer Research tool N.A. University of Innsbruck [1]
References
1 The influence of antibody humanization on shark variable domain (VNAR) binding site ensembles. Front Immunol. 2022 Sep 2;13:953917.