General Information of Synthetic Binding Protein (SBP) (ID: SBP003494)
SBP Name
Miniprotein anti-PD-L1 DBL1_03
Synonyms
DBL2_02
Molecular Weight 11.2 kDa
Design Method de novo protein design
Expression System Escherichia coli
Selection Method Yeast display
Highest Status Research
PDB ID 7XAD
Sequence Length 97
SBP Sequence
>DBL2_02
NLLTSYEGSFKIQLILAKLELAKAPSQPLSQRNEELKRVEQRQDRLFDLLDQMDVEVNNS
IGDASERATYKAKLREWKKTIQSDIKRPLQSLVDSGD
3D Structure
Experimentally Validated Structure
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Template Name yeast Vti1p_Habc domain
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Programmed cell death 1 ligand 1
BTS Info
binder Research tool Kd: 374 nM cole Polytechnique Fdrale de Lausanne [1]
References
1 De novo design of protein interactions with learned surface fingerprints