General Information of Synthetic Binding Protein (SBP) (ID: SBP003491)
SBP Name
Miniprotein anti-SARS-CoV-2 DBC2_01
Synonyms
DBR3_03
Molecular Weight 7.4 kDa
Design Method de novo protein design
Expression System Escherichia coli
Selection Method Yeast display
Highest Status Research
PDB ID 7ZSS
Sequence Length 66
SBP Sequence
>DBR3_03
STNMLEALQQRLQFYHGQVARAALENNSGKARRFGRIVKQYEDAIKLYKAGKPVPYDELP
VPPGFG
3D Structure
Experimentally Validated Structure
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Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Spike glycoprotein
BTS Info
binder Tools for inhibiting the ACE2CRBD interaction Kd: 80 nM cole Polytechnique Fdrale de Lausanne [1]
References
1 De novo design of protein interactions with learned surface fingerprints