General Information of Synthetic Binding Protein (SBP) (ID: SBP003490)
SBP Name
Miniprotein anti-SARS-CoV-2 DBP52_01
Synonyms
DBR3_02
Molecular Weight 7.4 kDa
Design Method de novo protein design
Expression System Escherichia coli
Selection Method Yeast display
Highest Status Research
Sequence Length 66
SBP Sequence
>DBR3_02
STNMLEALQQRLQFYFGVVSRAALENNSGKARRFGRIVKQYEDAIKLYKAGKPVPYDELP
VPPGFG
3D Structure
Computationally Modelled Structure
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Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Spike glycoprotein
BTS Info
binder Tools for inhibiting the ACE2CRBD interaction Kd: 4600 nM cole Polytechnique Fdrale de Lausanne [1]
References
1 De novo design of protein interactions with learned surface fingerprints