General Information of Synthetic Binding Protein (SBP) (ID: SBP003465)
SBP Name
Nanobody anti-SARS-CoV-2 MR17-K99Y
Synonyms
Nanobody MR17-K99Y; sybody MR17-K99Y
Molecular Weight 15.4 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
PDB ID 7CAN
Sequence Length 140
3D Structure
Experimentally Validated Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS048
Scaffold Info
[1]
Scaffold Name Nanobody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Spike glycoprotein
BTS Info
Binder SARS-CoV-2 infection (COVID-19) [ICD-11: XN109] N.A. N.A. [1]
References
1 Protein Data Bank. (7CAN)Structure of sybody MR17-K99Y in complex with the SARS-CoV-2 S Receptor-binding domain (RBD)