General Information of Synthetic Binding Protein (SBP) (ID: SBP003464)
SBP Name
Nanobody anti-SARS-CoV-2 NM1228
Synonyms
Nanobody NM1228
Molecular Weight 14.6 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Sequence Length 134
Protein Scaffold Information of This SBP
Scaffold ID PS048
Scaffold Info
[1]
Scaffold Name Nanobody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Spike glycoprotein
BTS Info
Inhibitor SARS-CoV-2 infection (COVID-19) [ICD-11: XN109] Kd: 1.4 nM Eberhard Karls University [1]
References
1 NeutrobodyPlex-monitoring SARS-CoV-2 neutralizing immune responses using nanobodies. EMBO Rep. 2021 May 5;22(5):e52325.