General Information of Synthetic Binding Protein (SBP) (ID: SBP003455)
SBP Name
Nanobody anti-US28Nb7 B1
Synonyms
Nanobody B1; NbB1
Molecular Weight 14.2 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Yeast display
Highest Status Research
PDB ID 5WB2
Sequence Length 131
SBP Sequence
>Nanobody anti-CX3CL1.35 B1
QLQLVESGGGLVQPGGSLRLSCAASGYSLEYYAIGWFRQAPGKEREGVSCISTSVGSTKY
ADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCGADLSTFYGGNYYCGDRGIYDYYG
QGTQVTVSSRG
3D Structure
Experimentally Validated Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS048
Scaffold Info
[1]
Scaffold Name Nanobody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
G-protein coupled receptor homolog US28
BTS Info
Binder Research tool N.A. Stanford University School of Medicine [1]
References
1 Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy. Elife. 2018 Jun 8;7:e35850.