General Information of Synthetic Binding Protein (SBP) (ID: SBP003447)
SBP Name
Nanobody anti-SARS-CoV-2 Nanosota-1
Synonyms
Nanosota-1C
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Bacteria
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS048
Scaffold Info
[1]
Scaffold Name Nanobody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Spike glycoprotein
BTS Info
Neutralizer SARS-CoV-2 infection (COVID-19) [ICD-11: XN109] Kd: 0.016 nM University of Minnesota [1]
References
1 The Development of a Novel Nanobody Therapeutic for SARS-CoV-2.bioRxiv. 2020 Nov 17;2020.11.17.386532.