General Information of Synthetic Binding Protein (SBP) (ID: SBP003293)
SBP Name
scFv anti-alpha-syn D5E
Synonyms
scFv D5E
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Alpha-synuclein
BTS Info
Binder Parkinson disease [ICD-11: 8A00.0] N.A. Arizona State University [1]
References
1 Fusion to a highly charged proteasomal retargeting sequence increases soluble cytoplasmic expression and efficacy of diverse anti-synuclein intrabodies. MAbs. Nov-Dec 2012;4(6):686-93.