Details of the SBP | SYNBIP

General Information of Synthetic Binding Protein (SBP) (ID: SBP003281)
SBP Name	scFv anti-BAFF ABL-1
Synonyms	scFv ABL-1
Molecular Weight	24.8 kDa
Design Method	Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System	Escherichia coli BL21 (DE3)
Highest Status	Research
Sequence Length	235
SBP Sequence	>scFv anti-BAFF ABL-1 VQLQESGGGLVQPGGSLRLSCATSGFTFTDYVMSWVRQPPGKALEWLGFIRNKANGYTTE YSASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYCARDITLLGQGTTVTVSSGGGGSG GGGSGGGGSDIELTQSPAIMSASLGERVTMTCTASSSVSSSYLHWYQQKPGSSPKLWIYS TSNLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCHQYHRSPYTFGGGTKLE
3D Structure
	Computationally Modelled Structure
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Template Name	Monoclonal antibody ABL-1

Protein Scaffold Information of This SBP
Scaffold ID	PS057 Scaffold Info					[1]
Scaffold Name	scFv
Scaffold Class	Antibody fragment
Fold Type	Beta-Sheets + Loops

Binding Target(s) of This SBP (BTS)

BTS Name	Details	Mechanism	Application	Affinity	Research Organization	Ref
Tumor necrosis factor ligand superfamily member 13B	BTS Info	Binder	Research tool	Kd: 9 nM	Nanjing Normal University	[1]

References

1

Production and characterization of a bacterial single-chain antibody fragment specific to B-cell-activating factor of the TNF family. Protein Expr Purif. 2005 Oct;43(2):157-64.