General Information of Synthetic Binding Protein (SBP) (ID: SBP003260)
SBP Name
scFv anti-C3 KF7
Synonyms
scFv KF7
Molecular Weight 25.2 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display
Highest Status Research
Sequence Length 242
SBP Sequence
>scFv anti-C3 KF7
QSLEESGGRLVTPGTPLTLTCTVSGFSLSTYAMSWVRQAPGKGLEWIGTITTGGGAYYAS
WAKGRFSISKTSTTVDLKITSPTTEDTATYFCARVNAGAGSYDYDYYFNFWGQGTLVTGG
GGSGGGGSGGGGSDLDMTQTPASVSEPVGGTVTIKCQASQSIGINLAWYQQKPGQPPKLL
IYQASKLASGVPSRFKGSRSGTEYTLTISDLECADAATYYCQQGYTGSNVENVFGGGTEV
VK
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Complement C3
BTS Info
Binder Research tool N.A. Medical School Hannover [1]
References
1 Guinea pig C3 specific rabbit single chain Fv antibodies from bone marrow, spleen and blood derived phage libraries. J Immunol Methods. 2000 Mar 6;236(1-2):117-31.