General Information of Synthetic Binding Protein (SBP) (ID: SBP003142)
SBP Name
Nanobody anti-SARS-CoV-2 1B-3F-2A
Synonyms
Nanobody 1B-3F-2A
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Expi293 cells
Selection Method Flow cytometry
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS048
Scaffold Info
[1]
Scaffold Name Nanobody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Spike glycoprotein
BTS Info
Neutralizer SARS-CoV-2 infection (COVID-19) [ICD-11: XN109] Kd: 0.095 nM Ab Studio Inc [1]
References
1 Development of humanized tri-specific nanobodies with potent neutralization for SARS-CoV-2. Sci Rep. 2020 Oct 20;10(1):17806.