Details of the SBP
General Information of Synthetic Binding Protein (SBP) (ID: SBP003127) | ||||||
---|---|---|---|---|---|---|
SBP Name |
Anticalin anti-CD98 P3D11
|
|||||
Synonyms |
Anticalin P3D11
|
|||||
Molecular Weight | 20.3 kDa | |||||
Thermal Denaturation TEMP | 55.2 ℃ | |||||
Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
Expression System | Escherichia coli | |||||
Selection Method | Phage display | |||||
Highest Status | Research | |||||
PDB ID | 6S8V | |||||
Sequence Length | 180 | |||||
SBP Sequence |
>Anticalin anti-CD98 P3D11
QDSTSDLIPAPPLSKVPLQQNFQDNQFHGKWYVVGRAGNTGLREDKDPGKMFATIYELKE DKSYNVTYVWFGQKKCMYSIGTFVPGSQPGEFTLGNIKSAPGRTSWLVRVVSTNYNQHAM VFFKSVTQNREGFAITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDGSA |
|||||
3D Structure | ||||||
Experimentally Validated Structure | ||||||
Click to Save PDB File | ||||||
Template Name | Lipocalin 2 (Lcn2) | |||||
Protein Scaffold Information of This SBP | ||||||
---|---|---|---|---|---|---|
Scaffold ID | PS011 | [1] | ||||
Scaffold Name | Anticalin | |||||
Scaffold Class | Non-Antibody | |||||
Fold Type | One Alpha-Helix + Beta-Sheets + Loops | |||||
Binding Target(s) of This SBP (BTS) |
---|
BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
---|---|---|---|---|---|---|
4F2 cell-surface antigen heavy chain | Binder | Imaging agent | Kd: 0.15 nM | Technical University of Munich | [1] | |