Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001821) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-RAGE M4
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| Synonyms |
scFv M4
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| Molecular Weight | 30 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Selection Method | Phage display and Ribosome display | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>VH Chain
EVQLVESGGGLVQPGGSLRLSCAASGFTFNNYWMTWVRQAPGKGLEWVASIDNSGDNTYY PDSVKDRFTISVKDRFTISDNAKNSLYLQMNSLRAEDTAVYYCARGGDITTGFDYWGQGT LVTVSS >VL Chain DIQMTQSPSSLSASVGDRVTITCRASQDVGIYVNWFQQKPGKAPRRLIYRATNLADGVPS RFSGSRSGTDFTLTISSLQPEDFATYYCLEFDEHPLTFGGGTKVEIK |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Advanced glycosylation end product-specific receptor | Binder | Research tool | IC50: 33 nM | University College Dublin | [1] | |