General Information of Synthetic Binding Protein (SBP) (ID: SBP001820)
SBP Name
scFv anti-TB B4m3
Synonyms
scFv B4m3
Molecular Weight 24.7 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Selection Method Surface plasmon resonance
Highest Status Research
Sequence Length 245
SBP Sequence
>scFv anti-TB B4m3
AVTLDESGGGLRTPGGGLSLVCKASGFDFSSYGMNWVRQAPGKGLEWVAGISGAGRYTGY
GAAVKGRATISRDNGQSTVRLQLNNLRAEDTGTYYCAKDAINYCCDVDSIDAWGHGTEVI
VSSGGGGSGGGGSGGGGSALTQPSSVSGNPGETVKITCSGGGSYAGSYYYGWYQQKSPGS
APVTVIYGNDKRPSDIPSRFSGSKSGSTATLTIAGVQAEDEAVYYCGSYEGSTGFGAGTT
LTVLG
3D Structure
Computationally Modelled Structure
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Template Name scFv B4
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Alpha-crystallin
BTS Info
Binder Research tool N.A. Onderstepoort Veterinary Institute [1]
References
1 Improving the characteristics of a mycobacterial 16 kDa-specific chicken scFv. Biologicals. 2011 Mar;39(2):110-6.