Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001805) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-IL-18 clone 40
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| Synonyms |
scFv h18-40
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| Molecular Weight | 27 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli JM83 | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>VH Chain
QVQLQQSGPGLVTPSQTLSLTCAISGDSVSSNRVTWNFIRQSPSRGLEWLGRTYYRSKWY NDFAVSVKSRITINPDTSKNQFSLQLNSVTPEDTAVYYCARDDSISWPPAPFDYWGQRTL VTVS >VL Chain ETTLTQSPSSVSASVGDRVTITCRASQDISNSLAWYHQEPGKAPKLLIYSVSTLESGVPS RFSGSGSGADFALTISNLQPEDFGTYYCQQAKSFPLTFGQGTKLEIK |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Interleukin-18 | Blocker | Inflammation [ICD-11: 1A00-CA43.1] | N.A. | Kagoshima University | [1] | |