Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001789) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-PSA M-PSA1
|
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| Synonyms |
scFv M-PSA1
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli MC1061 F | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>VH CDR1
SYLMN >VH CDR2 WITPSGGSTN >VH CDR3 ARYAGEFDV >VL CDR1 YLA >VL CDR3 QQDYYNPL |
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| Template Name | Human germline VH3 (IGHV3-23/DP-47) and Vgamma3 (IGKV3-20/A27) | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Prostate-specific antigen | Binder | Research tool | Kd: 5.3 nM | University of Turku | [1] | |