Details of the SBP | SYNBIP

General Information of Synthetic Binding Protein (SBP) (ID: SBP001714)
SBP Name	scFv anti-CD105 C4
Synonyms	scFv C4
Design Method	Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method	Phage display
Highest Status	Research

Protein Scaffold Information of This SBP
Scaffold ID	PS057 Scaffold Info					[1] , [2]
Scaffold Name	scFv
Scaffold Class	Antibody fragment
Fold Type	Beta-Sheets + Loops

Binding Target(s) of This SBP (BTS)

BTS Name	Details	Mechanism	Application	Affinity	Research Organization	Ref
Endoglin	BTS Info	Binder	Research tool	N.A.	University of Marburg	[1] , [2]

References

1	Isolation of endothelial cell-specific human antibodies from a novel fully synthetic scFv library. Biochem Biophys Res Commun. 2004 Apr 30;317(2):515-21.
2	Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105). Mol Ther. 2001 Jun;3(6):882-91.