Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001692) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-HBV clone 2
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| Synonyms |
ScFv-2
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| Molecular Weight | 26 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Selection Method | Escherichia coli display | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>VH CDR1
GFIFSGSSLH >VH CDR2 RIRPRADNYATAYAASMKG >VH CDR3 TMFSQKET >VL CDR1 RASQGISSWLA >VL CDR2 GASTLQN >VL CDR3 ITIHTKHNK |
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| Template Name | ScFv-31 | |||||
| Template Sequence |
>VH CDR1
GFIFSGSSLH >VH CDR2 RIRPRADNYATAYAASMKG >VH CDR3 FDWGTSLI >VL CDR1 RASQGISSWLA >VL CDR2 GASTLQN >VL CDR3 QQAYSFPYT |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] , [2] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Large envelope protein | Neutralizer | Hepatitis B virus infection [ICD-11: XN0GA] | N.A. | Northeast Agricultural University; Heilongjiang River Fishery Research Institute Chinese Academy of Fishery Sciences | [1] , [2] | |
| Infectious pancreatic necrosis virus ChRtm213 | Neutralizer | Hepatitis B virus infection [ICD-11: XN0GA] | N.A. | Northeast Agricultural University; Heilongjiang River Fishery Research Institute Chinese Academy of Fishery Sciences | [1] , [2] | |