Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001688) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-IL-33 A-5
|
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| Synonyms |
scFv A-5
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli HB2151 | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>VH Chain
RSRRCSCRSGGGVKAGGSRSCAGSGTNYIMSWVRAGKGWVSSINTGGAHMNYADAVKGRT ISRDDARNSHMHRRADTAYYCARGTRHCTTTYCDYYYMDVWGKGTTVTVSS >VL Chain NMTHSVSSKTRVTISCTRSSGSIASNYVWYRGSATTVIYDNRSGVDRSGIDSSGNSASTT IGKTSDDTYYCYDSSNVVGGTITVGAA |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Interleukin-33 | Inhibitor | Inflammation [ICD-11: 1A00-CA43.1]; Allergy [ICD-11: 4A80-4A85] | Kd: 41.5 nM | Luzhou Medical College | [1] | |