General Information of Synthetic Binding Protein (SBP) (ID: SBP001671)
SBP Name
scFv anti-BSA-O-polysaccharide B5-6
Synonyms
scFv B5-6
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Selection Method Phage display
Highest Status Research
SBP Sequence
>VH Chain
M34, Q43, E46, N55, G56, A57, T77, Y104, G109
>VL Chain
N54, S94, N96
Template Name scFv SK4
Template Sequence
>VH Chain
M34, Q43, E46, N55, S56, A57, I77, Y104, G109
>VL Chain
N54, S94, N96
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Albumin
BTS Info
Binder Research tool N.A. National Research Council of Canada [1]
References
1 Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene libraries. Proc Natl Acad Sci U S A. 1995 May 23;92(11):4992-6.