General Information of Synthetic Binding Protein (SBP) (ID: SBP001658)
SBP Name
scFv anti-Digoxigenin C8
Synonyms
scFv C8
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli FA113
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Digoxigenin
BTS Info
Binder Research tool Kd: 7.2 nM University of Texas [1]
References
1 A scFv antibody mutant isolated in a genetic screen for improved export via the twin arginine transporter pathway exhibits faster folding. J Mol Biol. 2007 Jun 8;369(3):631-9.