Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001651) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-MDM2 M1-19a
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| Synonyms |
scFv M1-19a
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| Molecular Weight | 25.1 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | mRNA display | |||||
| Highest Status | Research | |||||
| Sequence Length | 229 | |||||
| SBP Sequence |
>scFv anti-MDM2 M1-19a
QVQLQQSGPQLVRHGASMKISCKASGYSFTSYWMHWEQRSGLGLECIGMIDPSDSETRLN LKFKDKATLNVDKSSSTAYMQLSSPTSEDASVYYCARSETFYGNHGYFDVWGAGTALTVS SDIQMTQTTSSLSASLGDRVTISCSASQGISNYLNLYQQKPDGTVKLLIYYTSSLHSGVP SRFNGSGSGTDYSLTISNLEPEAIATYYCQQYSKPPPTFGGGTKLWIKR |
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| 3D Structure | ||||||
| Computationally Modelled Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| E3 ubiquitin-protein ligase Mdm2 | Binder | Research tool | Kd: 0.34 nM | Keio University | [1] | |