General Information of Synthetic Binding Protein (SBP) (ID: SBP001632)
SBP Name
scFv anti-HlyE C2
Synonyms
scFv C2
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display
Highest Status Research
SBP Sequence
>VH CDR1
GYTFTGYY
>VH CDR2
IIPIFGTA
>VH CDR3
ARCDYDILTGLYYYYGMDV
>VL CDR1
QSLLHSNGYNY
>VL CDR2
LGS
>VL CDR3
MQALQAPRT
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Hemolysin E
BTS Info
Binder Typhoid fever [ICD-11: 1A07] N.A. Universiti Sains Malaysia [1]
References
1 Delineation of B-cell Epitopes of Salmonella enterica serovar Typhi Hemolysin E: Potential antibody therapeutic target. Sci Rep. 2017 May 19;7(1):2176.