General Information of Synthetic Binding Protein (SBP) (ID: SBP001576)
SBP Name
Fab anti-Glycoprotein-F RSVF2-5
Synonyms
Fab RSVF2-5
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Fusion glycoprotein F0
BTS Info
Neutralizer Human respiratory syncytial virus infection [ICD-11: XN275] N.A. National Institutes of Health [1]
References
1 Isolation of a second recombinant human respiratory syncytial virus monoclonal antibody fragment (Fab RSVF2-5) that exhibits therapeutic efficacy in vivo. J Infect Dis. 1998 Apr;177(4):1073-6.