General Information of Synthetic Binding Protein (SBP) (ID: SBP001573)
SBP Name
Fab anti-Testosterone LCDR2 1D7
Synonyms
Fab LCDR2 1D7
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli RV308
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Testosterone
BTS Info
Binder Research tool N.A. VTT Biotechnology and Food Research [1]
References
1 Fine tuning of an anti-testosterone antibody binding site by stepwise optimisation of the CDRs. Immunotechnology. 1998 Jun;4(1):59-69.