Details of the SBP

General Information of Synthetic Binding Protein (SBP) (ID: SBP001534)
SBP Name
Fab anti-Glycoprotein-F clone 19
Synonyms
Fab 19
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Fusion glycoprotein F0
BTS Info
Binder Human respiratory syncytial virus infection [ICD-11: XN275] N.A. National Institutes of Health [1]
References
1 Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice. Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1386-90.