General Information of Synthetic Binding Protein (SBP) (ID: SBP001508)
SBP Name
Fab anti-Progesterone-BSA B6
Synonyms
Fab B6
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display
Highest Status Research
SBP Sequence
>Heavy Chain
QVKLLESGGGLVQPGGSLKLSCAASGFDFSRYWMSWVRQAPGKGLEWIGEINPDSSTINY
TPSLKDKFIISRDNAKNTLYLQMSKVRSEDTALYYCARRGVKTTCFAYWGQGTLVTVSS
>Light Chain
ELVLTQSPAIMSASPGEKVTMTCTASSSVSSSYLEWYQQKPGSSPQLWIYRTSNLASGVP
PRLSGSGSGTSYSLTISSMEAEDAATYYCHQYHRSPWTFGGGTKLEIK
Template Name scFv
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Albumin
BTS Info
Binder Research tool N.A. Scripps Research Institute [1]
References
1 In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3576-80.