General Information of Synthetic Binding Protein (SBP) (ID: SBP001507)
SBP Name
Fab anti-Progesterone-BSA A11
Synonyms
Fab A11
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display
Highest Status Research
SBP Sequence
>Heavy Chain
QVKLLESGAELVRPGASVKISCKAFGYTFTNHHINWVKQRPGQGLDWIGYINPYNDYTSY
NQKFKGKATLTVDKSSSTAYMELSSLTSEDSAVYYCARYYDYDGKGYYFDYWGQGTTLTV
SS
>Light Chain
ELVMTQSPSSLSASLGERVDLTCRASQDIGSSLNWLQQEPDGTIKRLIYATSSLDSGVPK
RFSGSRSGSDYSLTISSLESEDFVDYYCLQYASSPLTFGAGTKLELK
Template Name scFv
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Albumin
BTS Info
Binder Research tool N.A. Scripps Research Institute [1]
References
1 In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3576-80.