General Information of Synthetic Binding Protein (SBP) (ID: SBP001459)
SBP Name
DARPin anti-IgG-Fc I19
Synonyms
DARPin I19
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Lactococcus lactis cells
Selection Method LysM-mediated lactococcus lactis surface display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS027
Scaffold Info
[1]
Scaffold Name DARPin
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Fc fragment of human immunoglobulin G
BTS Info
Binder Research tool N.A. University of Ljubljana [1]
References
1 Improvement of LysM-mediated surface display of designed ankyrin repeat proteins (DARPins) in recombinant and nonrecombinant strains of Lactococcus lactis and Lactobacillus Species. Appl Environ Microbiol. 2015 Mar;81(6):2098-106.